| Identification | Back Directory | [Name]
1-[4-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]-ethanone | [CAS]
635703-12-7 | [Synonyms]
GPV574
GPV574 >=98% (HPLC)
1-[4-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]-ethanone
Ethanone, 1-[4-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]- | [Molecular Formula]
C23H30N2O3 | [MDL Number]
MFCD20527325 | [MOL File]
635703-12-7.mol | [Molecular Weight]
382.5 |
| Chemical Properties | Back Directory | [Boiling point ]
575.5±50.0 °C(Predicted) | [density ]
1.134±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥10mg/mL (warmed to 60°C) | [form ]
powder | [pka]
13.91±0.20(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
GPV574 is a derivative of the antiarrhythmic compound propafenone, capable of inhibiting HERG channels (IC50 = 5.04 μM).[1] | [References]
[1] Windisch A, et al. Trapping and dissociation of propafenone derivatives in HERG channels[J]. British journal of pharmacology, 2011, 162(7): 1542-1552. DOI:10.1111/j.1476-5381.2010.01159.x |
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| Company Name: |
Energy Chemical
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| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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