| Identification | More | [Name]
2-Methoxy-5-nitrophenol | [CAS]
636-93-1 | [Synonyms]
2-METHOXY-5-NITROPHENOL
3-HYDROXY-4-METHOXYNITROBENZENE
5-NITROGUAIACOL
NITROGUAIACOL(5-)
2-Hydroxy-1-methoxy-4-nitrobenzene
3-Hydroxy-4-methoxynitrobenzene~5-Nitroguaiacol
5-Nitroguaiacol (3-Hydroxy-4-methoxynitrobenzene)
2-Hydroxy-4-nitroanisole
5 nitroguaiacol, 2-methoxy-5-nitrophenol
Phenol, 2-methoxy-5-nitro-
2-Methoxy-5-nitrophenol 98%
2-METHOXY-5-NITROPHENOL/5-NITROGUAIACOL
2-METHOXY-5-NITROANILINE | [EINECS(EC#)]
211-269-0 | [Molecular Formula]
C7H7NO4 | [MDL Number]
MFCD00015561 | [Molecular Weight]
169.13 | [MOL File]
636-93-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
103-107 °C (lit.) | [Boiling point ]
110-112 °C/1 mmHg (lit.) | [density ]
1.3375 (estimate) | [refractive index ]
1.5830 (rough estimate) | [Fp ]
110-112°C/1mm | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
8.31±0.19(Predicted) | [color ]
Light Yellow to Light Brown | [Detection Methods]
HPLC | [BRN ]
2047074 | [InChI]
InChI=1S/C7H7NO4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3 | [InChIKey]
KXKCTSZYNCDFFG-UHFFFAOYSA-N | [SMILES]
C1(O)=CC([N+]([O-])=O)=CC=C1OC | [CAS DataBase Reference]
636-93-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [PackingGroup ]
III | [HS Code ]
29095090 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow to light brown powder | [Uses]
2-Methoxy-5-nitrophenol is used in the synthesis of potent VEGF and tyrosine kinase inhibitors. Also used in the synthesis of GABA analogues and phosphodiesterase inhibitors such as rolipram. | [Definition]
ChEBI: 2-Methoxy-5-nitrophenol is a member of 3-nitrophenols. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 28, p. 1287, 1980 DOI: 10.1248/cpb.28.1287 | [General Description]
2-Methoxy-5-nitrophenol is the substitution photoproduct formed on irradiation of 2-chloro-4-nitroanisole at 25°C in aqueous NaOH. |
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