| Identification | Back Directory | [Name]
azo analog I | [CAS]
64192-56-9 | [Synonyms]
azo analog I
SRIZDZJPKIYUPZ-ACGFIOGVSA-N
5-Heptenoic acid, 7-[(1R,4S,5R,6R)-6-(1E)-1-octen-1-yl-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl]-, (5Z)- | [Molecular Formula]
C20H32N2O2 | [MOL File]
64192-56-9.mol | [Molecular Weight]
332.48 |
| Chemical Properties | Back Directory | [Boiling point ]
463.1±34.0 °C(Predicted) | [density ]
1.10±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from U-46619); DMSO: >100 mg/ml (from U-46619); Ethanol: >100 mg/ml (from U-46619); PBS pH 7.2: >2 mg/ml (from U-46619) | [pka]
4.76±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
U-51605 is a platelet aggregation inhibitor and inhibits thromboxane synthesis. U-51605 is also a prostaglandin I2 synthase inhibitor and can inhibit the retinal vasodilation response induced by NO donors (such as NOR3)[1][2]. | [References]
[1] Needleman P, Bryan B, Wyche A, et al. Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions[J]. Prostaglandins, 1977, 14(5): 897-907.
[2] Mori A, Namekawa R, Hasebe M, et al. Involvement of prostaglandin I2 in nitric oxide-induced vasodilation of retinal arterioles in rats[J]. European Journal of Pharmacology, 2015, 764: 249-255. |
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Abcam Limited
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