| Identification | Back Directory | [Name]
Aceglatone | [CAS]
642-83-1 | [Synonyms]
Glucaron
Aceglatone
Aceglatone USP/EP/BP
Glucaro-(1→4:6→3)-dilactone diacetate
Furo[3,2-b]furan, D-glucaric acid deriv.
D-Glucaric acid, di-γ-lactone, 2,5-diacetate
2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone
O2,O5-diacetylglucaric acid 1,4:6,3-dilactone
Glucaric acid, di-γ-lactone, diacetate, D- (8CI)
Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI)
2-O,5-O-Diacetyl-D-glucaric acid 1,4:6,3-dilactone
2,5-di-O-Acetyl-D-glucosaccharo-(1→4:6→3)-dilactone
(2-acetyloxy-3,7-dioxo-4,8-dioxabicyclo[3.3.0]oct-6-yl) acetate | [Molecular Formula]
C10H10O8 | [MDL Number]
MFCD00079564 | [MOL File]
642-83-1.mol | [Molecular Weight]
258.18 |
| Hazard Information | Back Directory | [Uses]
Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1]. | [Definition]
ChEBI: Aceglatone is an organic molecular entity. | [References]
[1] Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats DOI:10.3892/mmr_00000022 |
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LGM Pharma
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1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
Alfa Chemistry
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+1 (201) 478-8534 |
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www.alfa-chemistry.com |
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