| Identification | Back Directory | [Name]
19(R)-HYDROXY PROSTAGLANDIN F2ALPHA | [CAS]
64625-53-2 | [Synonyms]
UBWZMPMLSDJDSU-OQRQNLQMSA-N
19(R)-hydroxy Prostaglandin F2α
19(R)-HYDROXY PROSTAGLANDIN F2ALPHA
9ALPHA,11ALPHA,15S,19R-TETRAHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
Prosta-5,13-dien-1-oic acid, 9,11,15,19-tetrahydroxy-, (5Z,9α,11α,13E,15S,19R)- | [Molecular Formula]
C20H34O6 | [MDL Number]
MFCD00135255 | [MOL File]
64625-53-2.mol | [Molecular Weight]
370.48 |
| Hazard Information | Back Directory | [Description]
19(R)-hydroxy PGF2α is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-hydroxy PGF compounds (F2α and F1α together) in fresh human semen is about 20 μg/ml.1 19(R)-hydroxy PGF2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.2 | [Uses]
19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM. | [Definition]
ChEBI: 19R-Hydroxy-PGF2alpha is a prostanoid. | [References]
1. Taylor, P.L., and Kelly, R.W. The occurrence of 19-hydroxy F prostaglandins in human semen FEBS Lett. 57(1),22-25(1975).
2. Woodward, D.F., Protzman, C.E., Krauss, A.H.P., et al. Identification of 19(R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist Prostaglandins 46(4),371-383(1993). |
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