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64657-18-7

64657-18-7 Structure

64657-18-7 Structure
IdentificationBack Directory
[Name]

1,9-DIDEOXYFORSKOLIN
[CAS]

64657-18-7
[Synonyms]

ddFSK
Dideoxyforskolin
9-Dideoxyforskolin
1,9-DIDEOXYFORSKOLIN
FORSKOLIN, 1,9-DIDEOXY
DIDEOXYFORSKOLIN, 1,9-
Dideoxyforskolin from Coleus forskohlii
FORSKOLIN, 1,9-DIDEOXY-, COLEUS FORSKOHLII
1,9-DIDEOXYFORSKOLIN FROM COLEUSFORSKOHL II
FORSKOLIN, 1,9-DIDEOXY ISOLATED FROM COL EUS
7β-acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one
7BETA-ACETOXY-8,13-EPOXY-6BETA-HYDROXY-LABD-14-EN-11-ONE
7BETA-ACETOXY-6BETA-HYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem
(3R,6aα,10bβ)-3,4aβ,7,7,10aβ-Pentamethyl-3α-vinyl-5β-acetoxy-6β-hydroxydodecahydro-1H-naphtho[2,1-b]pyran-1-one
(3R,6aα,10bβ)-5β-Acetoxy-3α-ethenyldodecahydro-6β-hydroxy-3,4aβ,7,7,10aβ-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
(3R,4aS,5S,6S,6aS,10aS,10bR)-6-hydroxy-3,4a,7,7,10a-pentaMethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chroMen-5-yl acetate
(3R,4aS,5S,6S,6aS,10aS,10bR)-5-(Acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
1H-Naphtho(2,1-B)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4A,7,7,10A-pentamethyl-, (3R,4as,5S,6S,6as,10as,10br)-
1H-Naphtho(2,1-B)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4A,7,7,10A-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10abeta,10balpha))-
[Molecular Formula]

C22H34O5
[MDL Number]

MFCD28125819
[MOL File]

64657-18-7.mol
[Molecular Weight]

378.5
Chemical PropertiesBack Directory
[Melting point ]

149-150℃
[storage temp. ]

−20°C
[solubility ]

methanol: 28 mg/mL
[form ]

solid
[color ]

white
[Optical Rotation]

[α]26/D +93.6°, c = 6.12 in chloroform(lit.)
[InChIKey]

ZKZMDXUDDJYAIB-OJPJTMFRSA-N
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H312
[Precautionary statements ]

P280-P302+P352-P312-P322-P363-P501
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.
[Uses]

1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
[Definition]

ChEBI: A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin.
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