| Identification | More | [Name]
Sodium deoxycholate | [CAS]
302-95-4 | [Synonyms]
17B-(1-METHYL-3-CARBOXYPROPYL)ETIOCHOLANE-3A,12A-DIOL SODIUM SALT
3A,12A-DIHYDROXYCHOLANIC ACID SODIUM SALT
3ALPHA,12ALPHA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID, SODIUM SALT
3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLANIC ACID SODIUM SALT
5-BETA-CHOLAN-24-OIC ACID-3A,12A-DIOLE SODIUM SALT
5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL SODIUM
5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL SODIUM SALT
7-DEOXYCHOLIC ACID SODIUM SALT
CHOLEIC ACID SODIUM SALT
DEOXYCHOLIC ACID NA-SALT
DEOXYCHOLIC ACID SODIUM SALT
DESOXYCHOLIC ACID SODIUM SALT
OXIDE EXTRACT
SODIUM CHOLEATE
SODIUM DEOXYCHOLATE
SODIUM DESOXYCHOLATE
(3-alpha,5-beta,12-alpha)-12-dihydroxy-cholan-24-oicacidmonosodiumsalt
3,12-dihydroxy-,monosodiumsalt,(3.alpha.,5.beta.,12.alpha.)-Cholan-24-oicacid
3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oicacisodiumsalt
cholan-24-oicacid,3,12-dihydroxy-,monosodiumsalt,(3-alpha,5-beta,12-alph | [EINECS(EC#)]
206-132-7 | [Molecular Formula]
C24H39NaO4 | [MDL Number]
MFCD00064139 | [Molecular Weight]
414.55 | [MOL File]
302-95-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to cream crystalline powder | [Melting point ]
357-365 °C
| [alpha ]
44 º (c=2, H2O) | [density ]
1.012 at 20.07℃ | [vapor pressure ]
0Pa at 20℃ | [Fp ]
>110°C (own results) | [storage temp. ]
Store at RT. | [solubility ]
water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow | [form ]
Powder | [color ]
Yellow-tan | [Odor]
Odorless | [PH]
7.5-9.0 (20g/l, H2O, 20℃) | [PH Range]
7 - 10 | [optical activity]
[α]20/D +44±2°, c = 2% in H2O | [Water Solubility ]
330 g/L (15 ºC) | [BRN ]
3581950 | [LogP]
5.35 at 22℃ and pH5.7 | [Surface tension]
41.8mN/m at 1g/L and 20℃ | [CAS DataBase Reference]
302-95-4(CAS DataBase Reference) | [EPA Substance Registry System]
302-95-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R37:Irritating to the respiratory system. | [Safety Statements ]
S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
FZ2250000
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
29181930 | [Safety Profile]
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO. | [Toxicity]
LD50 orally in Rabbit: 1370 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
Sodium deoxycholate is white to cream crystalline powder
| [Uses]
Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins.
| [Uses]
Sodium deoxycholate is used as a component in cell lysis buffers.
| [Definition]
ChEBI: Sodium deoxycholate is a bile acid salt. It contains a deoxycholate. | [General Description]
Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall. | [Biochem/physiol Actions]
Solubilizes fats for absorption in the intestines. | [Purification Methods]
Recrystallise it from EtOH and dry it in an oven at 100o. The solution is freed from soluble components by repeated extraction with acid-washed charcoal. [Beilstein 10 IV 1608.] |
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