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65213-48-1

65213-48-1 Structure

65213-48-1 Structure
IdentificationBack Directory
[Name]

(Z)-4-HYDROXYTAMOXIFEN
[CAS]

65213-48-1
[Synonyms]

4-OH-TAM
Tamoxifen Impurity 11
(Z)-4-HYDROXYTAMOXIFEN
trans-Hydroxytamoxifen
TAMOXIFEN, (Z)-4-HYDROXY-
TAMOXIFEN, 4-HYDROXY-, (Z)-
[Z]-1-[P-DIMETHYLAMINOETHOXYPHENYL]-1,2-DIPHENYL-1-BUTEN-4-OL
(Z)-4-[1-(P-(DIMETHYLAMINOETHOXY)PHENYL)-2-PHENYL-1-BUTENYL]PHENOL
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
(Z)-4-[1-[4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL]-2-PHENYL-1-BUTENYL-PHENOL
(Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)-phenyl)-2-phenylbut-1-en-1-yl)phenol
Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butenyl)-, (Z)-
(Z)-1-(4-Hydroxyphenyl)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butene
N,N-Dimethyl-2-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]ethanamine
N,N-Dimethyl-2-[p-[(Z)-1-(4-hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]ethanamine
[Molecular Formula]

C26H29NO2
[MDL Number]

MFCD00278780
[MOL File]

65213-48-1.mol
[Molecular Weight]

387.51
Chemical PropertiesBack Directory
[Melting point ]

137 - 143°C
[storage temp. ]

2-8°C
[solubility ]

95% ethanol: 20 mg/mL
[form ]

powder
[color ]

white
[Stability:]

Light Sensitive
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-63
[Safety Statements ]

22-23-36
[WGK Germany ]

3
[RTECS ]

SL1210000
Hazard InformationBack Directory
[Uses]

(Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen (T006000). (Z)-4-Hydroxy Tamoxifen is a hydroxylated analogue of Tamoxifen. (Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen with anti-estrogenic properties.
[Definition]

ChEBI: Afimoxifene is a tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. It has a role as an antineoplastic agent, an estrogen receptor antagonist and a metabolite. It is a tertiary amino compound and a member of phenols. It is functionally related to a tamoxifen.
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