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66-72-8

66-72-8 Structure

66-72-8 Structure
IdentificationBack Directory
[Name]

pyridoxal
[CAS]

66-72-8
[Synonyms]

pyridoxal
PYRIDOXALE
PYRIDOXALDEHYDE
Pyridoxal Labeled d3
3-hydroxy-2-methyl-5-methylol-isonicotinaldehyde
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde
3-Hydroxy-5-hydroxymethyl-2-methylpyridine-4-carbaldehyde
2-Methyl-3-hydroxy-5-(hydroxymethyl)pyridine-4-carbaldehyde
3-(Hydroxymethyl)-5-hydroxy-6-methylpyridine-4-carbaldehyde
3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarbaldehyde
4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-
[EINECS(EC#)]

200-630-8
[Molecular Formula]

C8H9NO3
[MDL Number]

MFCD00464806
[MOL File]

66-72-8.mol
[Molecular Weight]

167.16
Chemical PropertiesBack Directory
[Melting point ]

165 °C
[Boiling point ]

412.8±40.0 °C(Predicted)
[density ]

1.360±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[form ]

Solid
[pka]

pKa 4.20 (H2O t = 25 I = 0.1)(Approximate)
[color ]

White to off-white
[EPA Substance Registry System]

4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl- (66-72-8)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

4-Pyridoxic acid-->Pyridoxine-->Furo[3,4-c]pyridin-7-ol, 1-ethoxy-1,3-dihydro-6-methyl-
Hazard InformationBack Directory
[Definition]

ChEBI: A pyridinecarbaldehyde that is pyridine-5-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 4 respectively.
[Enzyme inhibitor]

This photosensitive aldehyde form of vitamin B6 (FW = 167.16 g/mol), systematically referred to as 3-hydroxy-5-(hydroxymethyl)-2-methyl-4- pyridinecarboxaldehyde, is the immediate precursor to the coenzyme pyridoxal 5’-phosphate (PLP) and is often a weaker competitive inhibitor of PLP binding to PLP-dependent enzymes). Pyridoxal is soluble in water (1 g/2 mL) and sensitive to heat, particularly at alkaline pH. The pKa values are 4.23 (phenol OH), 8.70 (pyridinium NH+), and 13.0. Pyridoxal has a lmax value of 252 nm at pH 7.0 (e = 8200 M–1cm–1). It is typically supplied as the hydrochloride. Target(s): O-acetylhomoserine aminocarboxypropyltransferase, or O-acetylhomoserine (thiol)-lyase; alanine racemase; aldehyde dehydrogenase; arginine decarboxylase; cystathionine b-lyase, or cystine lyase; cysteine synthase; dextransucrase; b-fructofuranosidase, or invertase; glutamate dehydrogenase; hemoglobin S polymerization; hydroxyacyl-glutathione hydrolase, or glyoxalase II; kynurenine 3- monooxygenase; lactoylglutathione lyase, or glyoxalase I; NMN nucleosidase; phosphopantothenoylcysteine decarboxylase; porphobilinogen synthase, or d-aminolevulinate dehydratase; pyridoxal kinase; pyridoxal phosphatase, weakly inhibited; starch phosphorylase; thiamin phosphatase; tyrosinase; and xanthine dehydrogenase.
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154-87-0 121-24-4 41468-25-1 65-22-5

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