| Identification | Back Directory | [Name]
Zeaenol | [CAS]
66018-41-5 | [Synonyms]
Zeaenol
LL Z1640-4
LL Z 1640 4,LLZ 16404
(5Z)-Zeaenol, Curvularia sp. - CAS 66018-41-5 - Calbiochem
1H-2-Benzoxacyclotetradecin-1-one, 3,4,7,8,9,10-hexahydro-7,8,9,16-tetrahydroxy-14-methoxy-3-methyl- (9CI) | [Molecular Formula]
C19H24O7 | [MDL Number]
MFCD14635375 | [MOL File]
66018-41-5.mol | [Molecular Weight]
364.39 |
| Chemical Properties | Back Directory | [Boiling point ]
636.3±55.0 °C(Predicted) | [density ]
1.275±0.06 g/cm3(Predicted) | [storage temp. ]
-20C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
White solid | [pka]
7.43±0.70(Predicted) | [color ]
white | [InChI]
1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,14-15,18,20-23H,5,8H2,1-2H3 | [InChIKey]
BPOLRDGTYHVUAY-UHFFFAOYSA-N | [SMILES]
O1C(CC=CC(C(C(CC=Cc2c(c(cc(c2)OC)O)C1=O)O)O)O)C |
| Hazard Information | Back Directory | [Uses]
LL Z1640-4 is a cis-enol resorcylic acid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, LL Z1640-2, containing the essential cis-enone system that selectively inhibits TAK 1, has gained literature focus. With its "inactive" cis-enol, LL Z1640-4 is an ideal negative control to help dissect the selectivity of the MAP kinases. | [General Description]
A cell-permeable resorcylic acid lactone compound that may serve as a negative control for TAK1 (TGF-β-Activated Kinase-1) inhibition studies. The active TAK1 inhibitor is also available, (5Z)-7-Oxozeaenol, Curvularia sp. (Cat. No. 499610). | [storage]
Store at -20°C |
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