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6656-19-5

6656-19-5 Structure

6656-19-5 Structure
IdentificationBack Directory
[Name]

DC037021
[CAS]

6656-19-5
[Synonyms]

DC037021
Isocanadine
6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-10,11-dimethoxy-
(+-)-2,3-methylenedioxy-10,11-dimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine
10,11-Dimethoxy-6,8,13,13a-tetrahydro-5H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline
[Molecular Formula]

C20H21NO4
[MOL File]

6656-19-5.mol
[Molecular Weight]

339.39
Chemical PropertiesBack Directory
[Melting point ]

177 °C
[Boiling point ]

468.8±45.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

6.55±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

LDLR regulator-1 (Compound 7b) is a regulator of the low-density lipoprotein receptor (LDLR), capable of increasing the mRNA expression of LDLR[1].
[References]

[1] Li Y H, et al. Berberine Analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure? activity relationships, and cholesterol-lowering efficacy[J]. Journal of Medicinal Chemistry, 2009, 52(2): 492-501. DOI:10.1021/jm801157z
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