| Identification | Back Directory | [Name]
ETHYL 3,4-DIHYDROXYCINNAMATE | [CAS]
66648-50-8 | [Synonyms]
Zinc01614326
ethyl (E)-caffeate
Ethyl trans-caffeate
E-Caffeic acid ethyl ester
Ethyl-3,4-dihydroxycinnamte
(E)-Ethyl Dihydroxycinnamate
ETHYL 3,4-DIHYDROXYCINNAMATE
Ethyl 3,4-dihydroxycinnamate,97%
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester, (2E)-
2-Propenoicacid,3-(3,4-dihydroxyphenyl)-,ethylester,(2E)-(9CI) | [Molecular Formula]
C11H12O4 | [MDL Number]
MFCD00045754 | [MOL File]
66648-50-8.mol | [Molecular Weight]
208.21 |
| Chemical Properties | Back Directory | [Melting point ]
147～151℃ | [Boiling point ]
148-149 °C | [density ]
1.271±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Off-white to brown solid. | [pka]
8.71±0.18(Predicted) | [color ]
White to off-white | [biological source]
plant | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C11H12O4/c1-2-15-11(14)6-4-8-3-5-9(12)10(13)7-8/h3-7,12-13H,2H2,1H3/b6-4+ | [InChIKey]
WDKYDMULARNCIS-GQCTYLIASA-N | [SMILES]
O(CC)C(=O)\C=C\c1cc(c(cc1)O)O | [LogP]
2.418 (est) |
| Hazard Information | Back Directory | [Uses]
Shows anti-carcinogenic, anti-inflammatory and immunomodulatory properties. Suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) production (IC50=5.5μg/ml). Potent and specific inhibitor of NF-κB and its downstream inflammatory mediators inducible nitric oxide synthase (iNOS; NOS II), prostaglandin E2 (PGE2) and cyclooxygenase-2 (COX-2). Prevents DNA single-strand breaks caused by H2O2. | [Definition]
ChEBI: Ethyl trans-caffeate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. It has a role as an anti-inflammatory agent and an antineoplastic agent. It is an alkyl caffeate ester and an ethyl ester. It is functionally related to a trans-caffeic acid. | [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | [Biological Activity]
Ethyl dihydroxycinnamate exhibits potent cytotoxicityinhibits COX-2 and P-hydroxybenzoic acidboth involved in inflammation and cytokine synthesis. It demonstrates antibacterial efficacy against MRSA and Bacillus subtilis and inhibits cancer cell growthcountering tumor formation. |
|
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
WG reagent
|
| Telephone: |
13391486464 |
| Website: |
www.wgchemical.com |
|