| Identification | Back Directory | [Name]
5-Propargylamino-3'-azidomethyl-dUTP | [CAS]
666847-57-0 | [Synonyms]
3'-O-azidomethyl-5-(3-amino-prop-1-ynyl)-2'-deoxyuridine 5'-O-nucleoside triphosphate | [Molecular Formula]
C13H19N6O14P3 | [MOL File]
666847-57-0.mol | [Molecular Weight]
576.24 |
| Hazard Information | Back Directory | [Description]
5-Propargylamino-3'-azidomethyl-dUTP is a key building block for preparing fluorescent conjugates that are used in the next generation sequencing (NGS).
| [Uses]
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing[1]. 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Milton J, et, al. Modified nucleotides for polynucleotide sequencing. WO2004018497A2. |
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