| Identification | Back Directory | [Name]
Cinobufaginol | [CAS]
6691-83-4 | [Synonyms]
Cinobufaginol
16β-(Acetyloxy)-14,15β-epoxy-3β,19-dihydroxy-5β-bufa-20,22-dienolide
Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,19-dihydroxy-, (3β,5β,15β,16β)- | [Molecular Formula]
C26H34O7 | [MDL Number]
MFCD31747005 | [MOL File]
6691-83-4.mol | [Molecular Weight]
458.54 |
| Chemical Properties | Back Directory | [Boiling point ]
639.012±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.347±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
14.967±0.70(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1]. | [References]
[1] Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371. DOI:10.1016/j.fitote.2019.03.006 |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
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13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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