| Identification | Back Directory | [Name]
tubotaiwine | [CAS]
6711-69-9 | [Synonyms]
NSC 306222
Tubotaiwin
tubotaiwine
20(S)-tubotaiwine
Methyl (14beta)-2,16-didehydrocondyfolan-16-carboxylate
2,16-Didehydrocondyfolan-16-carboxylic acid methyl ester
3,5-Ethano-3H-pyrrolo[2,3-d]carbazole-6-carboxylic acid, 4-ethyl-1,2,3a,4,5,7-hexahydro-, methyl ester, (3S,3aR,4S,5S,11bS)- | [Molecular Formula]
C20H24N2O2 | [MDL Number]
MFCD26406135 | [MOL File]
6711-69-9.mol | [Molecular Weight]
324.42 |
| Hazard Information | Back Directory | [Uses]
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling[1]. | [Definition]
ChEBI: A natural product found in Alstonia spatulata. | [References]
[1] Liwei Gao, et al. Protective Effect of Tubotaiwine on Cadmium-Induced Hypertension in Rats through Reduction in Arterial Stiffness and Vascular Remodeling. Dokl Biochem Biophys. 2021 Sep;500(1):368-375. DOI:10.1134/S1607672921050136 |
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