| Identification | Back Directory | [Name]
Hydrangel 8-O-glucoside | [CAS]
67600-94-6 | [Synonyms]
Hydrangel 8-O-glucoside
Hydrangenol 8-O-glucoside
hydrangenol 8-O-beta-D-glucopyranoside
3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-ylβ-D-glucopyranoside
1H-2-Benzopyran-1-one, 8-(β-D-glucopyranosyloxy)-3,4-dihydro-3-(4-hydroxyphenyl)-
8-(beta-D-Glucopyranosyloxy)-3,4-dihydro-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one | [Molecular Formula]
C21H22O9 | [MDL Number]
MFCD20261032 | [MOL File]
67600-94-6.mol | [Molecular Weight]
418.39 |
| Hazard Information | Back Directory | [Uses]
Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2]. | [Definition]
ChEBI: A member of the class of dihydroisocoumarins that is hydrangenol attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage. It has been isolated from the roots of Scorzonera judaica. | [References]
[1] Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2. DOI:10.1248/bpb.22.870
[2] Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254. DOI:10.3390/nu13010254 |
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