| Identification | Back Directory | [Name]
O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE | [CAS]
680622-70-2 | [Synonyms]
O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE
N-[4-(2-Amino-9H-purin-6-yloxymethyl)-benzyl]-2,2,2-trifluoroacetamide | [Molecular Formula]
C15H13F3N6O2 | [MDL Number]
MFCD09841373 | [MOL File]
680622-70-2.mol | [Molecular Weight]
366.298 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
211-213?C | [density ]
1.525±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.52±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine (cas# 680622-70-2) is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor. | [in vivo]
PIN1 inhibitor API-1 suppresses tumor growth in mice by up-regulating mature miRNA biogenesis[1]. |
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