| Identification | Back Directory | [Name]
LINOLEOYLETHANOLAMIDE | [CAS]
68171-52-8 | [Synonyms]
LEA
ODNHETOH
ANANDAMIDE
Einecs 269-029-6
LINOLEYLETHANOLAMIDE
Anandamide (18:2,n6)
LINOLEOYLETHANOLAMIDE
Linoleic ethanolamide
Linoleic ethanolamine
Linoleoyl monoethanolamide
N-lineleoyl Ethanolamide (LEA)
Monoethanolamine linoleic acid amide
9,12-Octadecadienamide, N-(2-hydroxyethyl)-
(9Z,12Z)-OCTADECA-9,12-DIENOLYLETHANOLAMIDE
N-(2-HYDROXYETHYL)-9Z, 12Z-OCTADECADIENAMIDE
n-(2-hydroxyethyl)-,(z,z)-12-octadecadienamide
(9Z,12Z)-N-(2-Hydroxyethyl)-9,12-octadecadienamide
(9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dienamide
(9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dien-1-amide
9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)-
(9Z,12Z)-N-(2-Hydroxyethyl)-9,12-octadecadienoic acidamide | [EINECS(EC#)]
269-029-6 | [Molecular Formula]
C20H37NO2 | [MDL Number]
MFCD00674434 | [MOL File]
68171-52-8.mol | [Molecular Weight]
323.51 |
| Chemical Properties | Back Directory | [Melting point ]
38-40 °C | [Boiling point ]
499.1±38.0 °C(Predicted) | [density ]
0.926±0.06 g/cm3(Predicted) | [Fp ]
14 °C | [storage temp. ]
-20°C | [solubility ]
DMF:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);154.55(Max Conc. mM) | [form ]
ethanol solution | [pka]
14.49±0.10(Predicted) | [color ]
Light yellow to light brown | [Stability:]
Light Sensitive, Temperature Sensitive | [Cosmetics Ingredients Functions]
SURFACTANT - FOAM BOOSTING
HAIR CONDITIONING
VISCOSITY CONTROLLING
ANTISTATIC | [InChI]
1S/C20H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h6-7,9-10,22H,2-5,8,11-19H2,1H3,(H,21,23)/b7-6-,10-9- | [InChIKey]
KQXDGUVSAAQARU-HZJYTTRNSA-N | [SMILES]
CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCO | [LogP]
6.003 (est) | [EPA Substance Registry System]
9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)- (68171-52-8) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xi | [Risk Statements ]
11-36/37/38 | [Safety Statements ]
16-26-36 | [RIDADR ]
UN 1170 3/PG 2 | [WGK Germany ]
1 | [TSCA ]
TSCA listed | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Eye Irrit. 2
Flam. Liq. 2 |
| Hazard Information | Back Directory | [Uses]
N-Linoleoylethanolamine reduces lipopolysaccharide-induced inflammation in macrophages and reduces inflammation in ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis. N-Linoleoylethanolamine inhibits NF-κB signaling and may be used as a therapeutic agent against contact dermatitis.Linoleoyl ethanolamide is an endocannabinoid detected in porcine brain. | [Definition]
ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of linoleic acid. | [Biochem/physiol Actions]
A structural analogue of the endogenous cannabinoid receptor ligand anandamide. | [in vivo]
Linoleoyl ethanolamide (0.1 mg-0.2 mg; challenged by painting the inner and outer surfaces of both sides of their ears) suppresses DNFB-induced ear swelling in BALB/c mice[3]. |
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