| Identification | Back Directory | [Name]
ANTI-CDC27 | [CAS]
682795-78-4 | [Synonyms]
APC3
CDC27
H-NUC
ANAPC3
CDC27Hs
D0S1430E
Anti-HNUC
Anti-APC3
ANTI-CDC27
Anti-D0S1430E
Anti-D17S978E
MONOCLONAL ANTI-CDC27
Anti-Cell division cycle 27
Anti-Anaphase promoting complex 3
Anti-APC3 antibody produced in rabbit
Anti-CDC27 antibody produced in rabbit
Anti-H-NUC antibody produced in rabbit
Cell division cycle protein 27 homolog
Anti-cell division cycle 27 homolog (S. cerevisiae)
Monoclonal Anti-Cdc27 antibody produced in mouse
2-Pyrimidinamine, 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]- | [Molecular Formula]
C22H23N3O4 | [MDL Number]
MFCD01633250 | [MOL File]
682795-78-4.mol | [Molecular Weight]
393.44 |
| Chemical Properties | Back Directory | [Boiling point ]
596.455±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.250±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
−20°C | [form ]
buffered aqueous solution | [pka]
3.777±0.10(predicted) | [biological source]
rabbit |
| Hazard Information | Back Directory | [Uses]
AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1]. | [References]
[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835 |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|