| Identification | Back Directory | [Name]
20-(tert-Butoxy)-20-oxoicosanoic acid | [CAS]
683239-16-9 | [Synonyms]
20-(tert-Butoxy)-20-oxoicosanoic acid
20-(tert-Butoxy)-20-Eicosanedioic Aci
Eicosanedioic acid 1-tert-butyl ester
Eicosanedioic acid mono-t-butyl ester
20-(tert-Butoxy)-20-Eicosanedioic Acid
Eicosanedioic acid Mono-tert-butyl Ester
Eicosandioic acid, 1-(1,1-dimethyl) ester
Eicosanedioic acid, 1-(1,1-dimethylethyl) ester
20-[(2-methylpropan-2-yl)oxy]-20-oxoicosanoic acid
20-(tert-Butoxy)-20-oxoicosanoic acid ISO 9001：2015 REACH | [EINECS(EC#)]
202-303-5 | [Molecular Formula]
C24H46O4 | [MDL Number]
MFCD23136041 | [MOL File]
683239-16-9.mol | [Molecular Weight]
398.62 |
| Chemical Properties | Back Directory | [Boiling point ]
496.0±18.0 °C(Predicted) | [density ]
0.942±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
4.78±0.10(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C24H46O4/c1-24(2,3)28-23(27)21-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-22(25)26/h4-21H2,1-3H3,(H,25,26) | [InChIKey]
JUCDAUSILDWYOA-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCCCC(O)=O | [CAS DataBase Reference]
683239-16-9 |
| Hazard Information | Back Directory | [Description]
20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and in the synthesis of PROTACs. | [Chemical Properties]
Eicosanedioic acid mono-tert-butyl ester is a solid at room temperature and pressure, with poor solubility in water but some solubility in alcohol organic solvents. It has certain acidity, and the carboxyl unit at one end of the alkyl chain in its structure can be esterified with alcohol compounds under the action of acid catalyst to obtain the corresponding diester derivatives. | [Uses]
20-(tert-Butoxy)-20-oxoicosanoic acid is a useful research chemical compound. | [Synthesis]
20-(tert-Butoxy)-20-oxoicosanoic acid can be prepared from eicosanedioic acid by esterification. | [IC 50]
Non-cleavable Linker |
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