| Identification | Back Directory | [Name]
1-Methyl-2-nonylquinolin-4(1H)-one | [CAS]
68353-24-2 | [Synonyms]
N-methyl-2-nonyl-4-quinolone
1-methyl-2-nonylquinolin-4-one
1-Methyl-2-nonyl-4-quinolinone
1-METHYL-2-NONYLQUINOLIN-4(1H)-O
1-Methyl-2-nonyl-4(1H)-quinolone
1-Methyl-2-nonyl-4(1H)-quinolinone
1-Methyl-2-nonylquinolin-4(1H)-one
1-Methyl-2-n-nonyl-4(1H) quinolone
4(1H)-Quinolinone, 1-methyl-2-nonyl- | [Molecular Formula]
C19H27NO | [MDL Number]
MFCD25371966 | [MOL File]
68353-24-2.mol | [Molecular Weight]
285.42 |
| Hazard Information | Back Directory | [Uses]
1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2]. | [Definition]
ChEBI: 1-Methyl-2-nonyl-4(1H)-quinolinone is a member of quinolines. | [IC 50]
MAO-B; MAO-A | [References]
[1] Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401. DOI:10.1007/BF02980210
[2] Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8. DOI:10.1055/s-2004-832614 |
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