| Identification | Back Directory | [Name]
Sarsasapogenin 3-O-β-D-galactopyranosid | [CAS]
68422-00-4 | [Synonyms]
TiMosaponin A1
Timosaponin AI
Sarsasapogenin 3-O-β-D-galactopyranosid
Sarsasapogenin 3-O-β-D-galactopyranoside
β-D-Galactopyranoside, (3β,5β,25S)-spirostan-3-yl
Sarsasapogenin 3-O-β-D-galactopyranosid USP/EP/BP | [Molecular Formula]
C33H54O8 | [MDL Number]
MFCD31706225 | [MOL File]
68422-00-4.mol | [Molecular Weight]
578.79 |
| Hazard Information | Back Directory | [Uses]
Timosaponin A1 exhibits a wide spectrum of bioactivities. Also, it is a metabolite of Timosaponin A3 (T444695), which suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator. |
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