| Identification | Back Directory | [Name]
pseudoprototimosaponin AIII | [CAS]
142759-74-8 | [Synonyms]
Timosaponin B
AneMarsaponin B3
AneMarsaponin BIII
pseudoprototimosaponin AIII
pseudoprototimosaponin BIII
PseudoprototiMosaponin AIII, AneMarrhenasaponin IV, AneMarsaponin B
b-D-Galactopyranoside, (3b,5b,25S)-26-(b-D-glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-b-D-glucopyranosyl-
β-D-Galactopyranoside, (3β,5β,25S)-26-(β-D-glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-β-D-glucopyranosyl- | [Molecular Formula]
C45H74O18 | [MDL Number]
MFCD29917564 | [MOL File]
142759-74-8.mol | [Molecular Weight]
903.06 |
| Chemical Properties | Back Directory | [Boiling point ]
1023.7±65.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.85±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Timosaponin B III is a major bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects[1][2][3]. | [References]
[1] Zhang XL, et al. Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity. Exp Ther Med. 2017 Oct;14(4):3856-3861. DOI:10.3892/etm.2017.4930
[2] Zhao YF, et al. New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III. Nat Prod Res. 2018 Nov 20:1-7. DOI:10.1080/14786419.2018.1499640
[3] Kang LP, et al. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplateletaggregation activity. Planta Med. 2012 Apr;78(6):611-6. DOI:10.1055/s-0031-1298223 |
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