| Identification | Back Directory | [Name]
BUSERELIN | [CAS]
68630-75-1 | [Synonyms]
Fuset
hoe766
EstoMal
Itorelin
Suprecur
hoe766mp
SupreMon
Buserecur
Suprafact
Suprecur-MP
buserelinacetate
BUSERELIN USP/EP/BP
Buserelina(acetate)
Buserelin Acetate, >99%
Buserelin?Acetate impurity
Buserelin acetate, Ph. Eur.
Buserelin acetate [USAN:JAN]
Buserelin Acetate, Buserelina
Buserelin for NMR identification
Buserelin for peak identification
Buserelin for NMR identification CRS
Buserelin for peak identification CRS
(DES-GLY10,D-SER(TBU)6,PRO-NHET9)-LHRH
des-gly10-[d-ser[t-bu]6]-lh-rh ethylamide
PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET
P-GLU-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET
9-(n-ethyl-l-prolinamide)-10-deglycinamide,monoacetate(salt)
6-(o-(1,1-dimethylethyl)-d-serine)-luteinizinghormone-releasingfactor(pig
pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt, des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide
6-[O-(1,1-DiMethylethyl)-D-serine]-9-(N-ethyl-L-prolinaMide)-1-9-luteinizing HorMone-releasing Factor Monoacetate
1-9-Luteinizing hormone-releasing factor (swine), 6-O-(1,1-dimethylethyl)-D-serine-9-(N-ethyl-L-prolinamide)-, monoacetate (salt) | [EINECS(EC#)]
636-185-5 | [Molecular Formula]
C62H90N16O15 | [MDL Number]
MFCD01716229 | [MOL File]
68630-75-1.mol | [Molecular Weight]
1299.5 |
| Chemical Properties | Back Directory | [Melting point ]
186-188°C | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic | [InChIKey]
PYMDEDHDQYLBRT-DRIHCAFSSA-N |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
60 | [Safety Statements ]
53-22-36/37/39-45 | [WGK Germany ]
3 | [RTECS ]
OK6370000 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 4 Oral
Repr. 1B |
| Hazard Information | Back Directory | [Description]
Buserelin acetate is a potent analog of the hypothalamic hormone, luteinizing
hormone-releasing hormone (LH-RH). Chronic administration of higher doses of
buserelin desensitizes the pituitary, resulting in a decreased production of
luteinizing hormone (LH), follicle stimulating hormone (FSH), and eventually
sex steroids (testosterone in males and estradiol in females). Initial approval is
for use in achieving medical castration in the treatment of advanced prostate
cancer. It has also been investigated for the treatment of endometriosis,
leiomyoma, precocious puberty, advanced breast cancer and infertility. | [Chemical Properties]
White Solid | [Originator]
Hoechst AG (W. Germany) | [Uses]
Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal). | [Definition]
ChEBI: Buserelin acetate is an organic molecular entity. | [Brand name]
Suprefact
(Hoechst-Roussel). | [Biochem/physiol Actions]
Buserelin is an LH-RH agonist. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Telephone: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|