| Identification | Back Directory | [Name]
PINOCEMBRIN | [CAS]
68745-38-0 | [Synonyms]
NSC 43318
PINOCEMBRIN
(±)-Pinocchio
DL-Pinocembrin
rac-PinoceMbrin
(+/-)-Pinocembrin
5,7-DIHYDROXYFLAVANONE
Pinocembrin racemate (DL0108)
5,7-DIHYDROXY-3'4'5'-FLAVANONE
5,7-Dihydroxy-2-phenyl-4-chromanone
5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE
5,7-Dihydroxyflavanone (Pinocembrin)
5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
2-Phenyl-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one
5,7-Dihydroxy-2,3-dihydro-2-phenyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-
(2R)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one | [Molecular Formula]
C15H12O4 | [MDL Number]
MFCD00017482 | [MOL File]
68745-38-0.mol | [Molecular Weight]
256.25 |
| Chemical Properties | Back Directory | [Melting point ]
202-203°C | [Boiling point ]
511.1±50.0 °C(Predicted) | [density ]
1.386±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly, heated), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.50±0.40(Predicted) | [color ]
White to Pale Beige | [Major Application]
food and beverages | [InChI]
1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1 | [InChIKey]
URFCJEUYXNAHFI-ZDUSSCGKSA-N | [SMILES]
OC1=CC(OC(C2=CC=CC=C2)C3)=C(C(O)=C1)C3=O |
| Hazard Information | Back Directory | [Uses]
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c. | [Synthesis]
The synthesis of biopinein was carried out by the traditional chalcone closed-loop synthetic route, which requires chemical reagents that have the disadvantage of polluting the environment, reacting under drastic conditions, and consuming large amounts |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
parabiochem
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| Telephone: |
025-83453382-8005 |
| Website: |
www.parabiochem.cn |
| Company Name: |
Henan Alfachem Co.,Ltd.
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| Telephone: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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