| Identification | Back Directory | [Name]
4-Oxobedfordiaic acid | [CAS]
68799-38-2 | [Synonyms]
4-Oxobedfordiaic acid
3-Cycloheptene-1-acetic acid, 5-methyl-α-methylene-4-(3-oxobutyl)-, (1R,5S)-
(1R-cis)-5-Methyl-alpha-methylene-4-(3-oxobutyl)-3-cycloheptene-1-acetic acid | [Molecular Formula]
C15H22O3 | [MOL File]
68799-38-2.mol | [Molecular Weight]
250.33 |
| Hazard Information | Back Directory | [Uses]
4-Oxobedfordiaic acid is an orally active natural product, that can be isolated from Xanthium cavanillesi. 4-Oxobedfordiaic acid shows anti-ulcerogenic activity[1]. | [in vivo]
4-Oxobedfordiaic acid (100 mg/kg, orally, single) shows gastroprotective effect on EtOH-induced lesions in rats, with a ulcer index of 1.33 ± 0.16 and an inhibition of 74%[1]. | [References]
[1] Favier LS, et al. Anti-ulcerogenic activity of xanthanolide sesquiterpenes from Xanthium cavanillesii in rats. J Ethnopharmacol. 2005 Sep 14;100(3):260-7. DOI:10.1016/j.jep.2005.02.042 |
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