ChemicalBook--->CAS DataBase List--->688348-33-6

688348-33-6

688348-33-6 Structure

688348-33-6 Structure
IdentificationBack Directory
[Name]

1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE
[CAS]

688348-33-6
[Synonyms]

CAY10465
CAY10465 Exclusive
CAY10465;CAY-10465;CAY 10465
1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE
1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene
[Molecular Formula]

C15H9Cl2F3
[MDL Number]

MFCD08062182
[MOL File]

688348-33-6.mol
[Molecular Weight]

317.13
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 20 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. CAY10465 is an analog of resveratrol acting as a potent and selective AhR agonist, with a Ki of 0.2 nM. CAY10465 is inactive as a ligand for the estrogen receptor even at 100 μM.
[Uses]

(E)-1-[4-(Trifluoromethyl)phenyl]-2-(3,5-dichlorophenyl)ethene is a stilbene derivative of resveratrol and a selective aryl hydrocarbon receptor agonist.
[storage]

Store at -20°C
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