| Identification | Back Directory | [Name]
Kv2-IN-A1 | [CAS]
689297-68-5 | [Synonyms]
Kv2-IN-A1
ry785，Kv2-IN-A1
Benzenepropanamide, 3-chloro-β-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]- | [Molecular Formula]
C20H17ClN4OS | [MDL Number]
MFCD28160785 | [MOL File]
689297-68-5.mol | [Molecular Weight]
396.89 |
| Hazard Information | Back Directory | [Description]
Kv2-IN-A1 is a Kv2.1 and Kv2.2 inhibitor. | [Uses]
KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels[1]. | [References]
[1] James Herrington, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64. DOI:10.1124/mol.111.074831 |
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Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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cjbscvictory
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https://www.weikeqi-biotech.com/ |
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