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69199-40-2

69199-40-2 Structure

69199-40-2 Structure
IdentificationBack Directory
[Name]

-triphosphate, Triethylammonium Salt) (1mM)
[CAS]

69199-40-2
[Synonyms]

-deoxy-uridine-5&rsquo
3'-Deoxyuridine-5'-triphosphate
-triphosphate, Triethylammonium Salt) (1mM)
4-dUTP (Biotin) (N-Biotin-5-(3-aminoallyl)-2&rsquo
11-dUTP (Biotin) (g-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2&rsquo
16-dUTP (Biotin) g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2&rsquo
[Molecular Formula]

C9H15N2O14P3
[MDL Number]

MFCD00070157
[MOL File]

69199-40-2.mol
[Molecular Weight]

468.14
Chemical PropertiesBack Directory
[density ]

2.010±0.06 g/cm3(Predicted)
[pka]

0.80±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].
[References]

[1] M Saneyoshi, et al. Inhibitory Effects of 3'deoxycytidine 5'-triphosphate and 3'-deoxyuridine 5'-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38. DOI:10.1093/nar/9.13.3129
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