Identification | Back Directory | [Name]
-triphosphate, Triethylammonium Salt) (1mM) | [CAS]
69199-40-2 | [Synonyms]
-deoxy-uridine-5&rsquo 3'-Deoxyuridine-5'-triphosphate -triphosphate, Triethylammonium Salt) (1mM) 4-dUTP (Biotin) (N-Biotin-5-(3-aminoallyl)-2&rsquo 11-dUTP (Biotin) (g-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2&rsquo 16-dUTP (Biotin) g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2&rsquo | [Molecular Formula]
C9H15N2O14P3 | [MDL Number]
MFCD00070157 | [MOL File]
69199-40-2.mol | [Molecular Weight]
468.14 |
Hazard Information | Back Directory | [Uses]
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. | [References]
[1] M Saneyoshi, et al. Inhibitory Effects of 3'deoxycytidine 5'-triphosphate and 3'-deoxyuridine 5'-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38. DOI:10.1093/nar/9.13.3129 |
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