| Identification | More | [Name]
LUTEOLIN-4'-O-GLUCOSIDE | [CAS]
6920-38-3 | [Synonyms]
3',4',5,7-TETRAHYDROXYFLAVONE-4'-GLUCOSIDE
LUTEOLIN-4'-GLUCOSIDE
LUTEOLIN-4'-O-GLUCOSIDE
2-(4-β-D-Glucopyranosyloxy-3-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
2-[3-Hydroxy-4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
3',5,7-Trihydroxy-4'-(β-D-glucopyranosyloxy)flavone
4'-β-D-O-Glucopyranosylluteolin | [Molecular Formula]
C21H20O11 | [MDL Number]
MFCD00017468 | [Molecular Weight]
448.38 | [MOL File]
6920-38-3.mol |
| Hazard Information | Back Directory | [Uses]
Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3]. | [IC 50]
IL-5 | [References]
[1] Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. DOI:10.1055/s-2006-960812
[2] Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. DOI:10.1016/j.phymed.2018.02.002
[3] Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237. |
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