| Identification | More | [Name]
12-AMINODODECANOIC ACID | [CAS]
693-57-2 | [Synonyms]
12-AMINODODECANOIC ACID
12-AMINOLAURIC ACID
ADA
H-12-ADO-OH
NH2-(CH2)11-COOH
DODECANOICACID,12-AMINO- | [EINECS(EC#)]
211-754-7 | [Molecular Formula]
C12H25NO2 | [MDL Number]
MFCD00008153 | [Molecular Weight]
215.33 | [MOL File]
693-57-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
185-187 °C (lit.) | [Boiling point ]
349.7±15.0 °C(Predicted) | [density ]
0.957±0.06 g/cm3(Predicted) | [vapor pressure ]
0Pa at 25℃ | [Fp ]
280 °C | [storage temp. ]
Store at 0°C | [solubility ]
Aqueous Acid (Slightly), Aqueous Base (Slightly) | [form ]
Solid | [pka]
pK1: 4.648(+1) (25°C) | [color ]
White to Off-White | [Water Solubility ]
137mg/L at 20℃ | [BRN ]
907502 | [Major Application]
peptide synthesis | [InChI]
1S/C12H25NO2/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h1-11,13H2,(H,14,15) | [InChIKey]
PBLZLIFKVPJDCO-UHFFFAOYSA-N | [SMILES]
NCCCCCCCCCCCC(O)=O | [LogP]
-0.607 at 24.6℃ | [CAS DataBase Reference]
693-57-2(CAS DataBase Reference) | [EPA Substance Registry System]
12-Aminolauric acid (693-57-2) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS08 | [Signal word ]
Warning | [Hazard statements ]
H373 | [Precautionary statements ]
P260-P314-P501 | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29224999 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Description]
12-Aminododecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond. | [Chemical Properties]
Light beige powder | [Uses]
12-Aminolauric Acid is an amino acid used as a reagent in organic synthesis of several compounds including phenylbutazone which is a new long-acting agent which displays improved pharmacokinectics based on human serum albumin as a drug carrier. | [Definition]
ChEBI: 12-aminododecanoic acid is an omega-amino fatty acid that is dodecanoic acid in which one of the terminal amino hydrogens has been replaced by an amino group. It has a role as a bacterial metabolite. It is an omega-amino fatty acid and a medium-chain fatty acid. | [Flammability and Explosibility]
Nonflammable | [reaction suitability]
reaction type: solution phase peptide synthesis |
|
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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Maya High Purity Chemicals
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