| Identification | Back Directory | [Name]
Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid | [CAS]
69907-67-1 | [Synonyms]
trans-4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)
Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
trans-4-(N-maleimidemethyl)cyclohexane-1-carboxylic acid
trans-4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)Methyl)cyclohexanecarboxylic acid
trans-4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexanecarboxylic acid
(1R,4R)-4-((2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)METHYL)CYCLOHEXANECARBOXYLIC ACID
Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)Methyl]-, trans- | [Molecular Formula]
C12H15NO4 | [MDL Number]
MFCD11519178 | [MOL File]
69907-67-1.mol | [Molecular Weight]
237.25 |
| Chemical Properties | Back Directory | [Melting point ]
144 °C(Solv: benzene (71-43-2)) | [Boiling point ]
433.6±18.0 °C(Predicted) | [density ]
1.329 | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
4.80±0.10(Predicted) | [color ]
White to Almost white | [CAS DataBase Reference]
69907-67-1 |
| Questions and Answers (Q&A) | Back Directory | [Description]
Trans-4-(Maleimidomethyl) cyclohexanecarboxylic Acid is a kind of carboxylate, being well known for its N-hydroxysuccinimide ester derivative (SMCC), which is a useful cross-linking reagent. SMCC is widely used for the generation of stable maleimide-activated carrier proteins, enzyme immunoconjugates and hapten carrier molecule conjugates. It can be used for the coupling of a peptide to an amino group.
| [References]
https://www.aatbio.com/products/smcc-4-n-maleimidomethyl-cyclohexanecarboxylic-acid-n-hydroxysuccinimide-ester-cas-64987-85-5
http://www.sigmaaldrich.com/catalog/product/sigma/m5525?lang=en®ion=US
Zhang, Hongyan, et al. "Antifreeze protein detection using Rhodamine B as photoluminescence label inporous silicon." Current Applied Physics13.4(2013):736-742.
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