| Identification | Back Directory | [Name]
4,10-Aromadendranediol | [CAS]
70051-38-6 | [Synonyms]
10-Aromadendranediol
4,10-Aromadendranediol
Aromadendrane-4β,10α-diol
Aromadendrane-4β,10α-diol
1H-Cycloprop[e]azulene-4,7-diol, decahydro-1,1,4,7-tetramethyl-, (1aR,4R,4aR,7S,7aS,7bR)- | [Molecular Formula]
C15H26O2 | [MDL Number]
MFCD20274807 | [MOL File]
70051-38-6.mol | [Molecular Weight]
238.37 |
| Hazard Information | Back Directory | [Uses]
Aromadendrane-4β,10α-diol is a sesquiterpene alcohol. Aromadendrane-4β,10α-diol significantly ameliorates the Aβ1-42 peptide-induced memory impairment. Aromadendrane-4β,10α-diol can be used for Alzheimer's disease (AD) research[1]. | [in vivo]
Aromadendrane-4β,10α-diol (1 μg/mouse, i.c.v.) significantly increases the activity of antioxidant enzymes (glutathione, GSH) and decreases of lipid peroxidation in Aβ1-42 (400 pmol/mouse, i.c.v.) mice[1]. | [References]
[1] Amoah SK, et al. Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer. Eur J Pharmacol. 2015 Dec 15;769:195-202. DOI:10.1016/j.ejphar.2015.11.018 |
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| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
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http://www.biobiopha.com |
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