| Identification | Back Directory | [Name]
Carbazeran | [CAS]
70724-25-3 | [Synonyms]
557
UK31
UK-31
UK 31
UK 31557
Carbazeran
Ethylcarbamic acid carbamic acid
1-(6,7-Dimethoxyphthalazin-1-yl)
1-(6,7-diMethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbaMate
EthylcarbaMic Acid 1-(6,7-DiMethoxy-1-phthalazinyl)-4-piperidinyl Ester
N-EthylcarbaMic Acid 1-(6,7-DiMethoxy-1-phthalazinyl)-4-piperidinyl Ester
Ethyl-carbamic acid 1-(6,7-dimethoxy-phthalazin-1-yl)-piperidin-4-yl ester
CarbaMic acid, N-ethyl-, 1-(6,7-diMethoxy-1-phthalazinyl)-4-piperidinyl ester | [Molecular Formula]
C18H24N4O4 | [MDL Number]
MFCD00867107 | [MOL File]
70724-25-3.mol | [Molecular Weight]
360.412 |
| Chemical Properties | Back Directory | [Boiling point ]
596℃ | [density ]
1.27 | [Fp ]
314℃ | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥2mg/mL at warmed | [form ]
powder | [pka]
12.72±0.46(Predicted) | [color ]
white to beige | [Stability:]
Hygroscopic | [InChI]
1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23) | [InChIKey]
QJGVXJYGDBSPSJ-UHFFFAOYSA-N | [SMILES]
CCNC(=O)OC1CCN(CC1)c2nncc3cc(OC)c(OC)cc23 |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
25 | [Safety Statements ]
45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow to Pale Brown Solid | [Uses]
Carbazeran is a phosphodiesterase inhibitor drug. Carbazeran shows chronotropic and inotropic effects. | [Biological Activity]
Carbazeran is an Aldehyde oxidase (AO) substrate and a phosphodiesterase inhibitor th at produces concentration-dependent positive inotropic responses. In humansthe compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO. |
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| Company Name: |
Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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