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708-53-2

708-53-2 Structure

708-53-2 Structure
IdentificationBack Directory
[Name]

2,3-DIHYDROXY-4-METHOXYACETOPHENONE
[CAS]

708-53-2
[Synonyms]

NSC 46636
2,3-Dihydroxy-4-Methoxyacetohpe
GALLACETOPHENONE-4-METHYL ETHER
Gallacetophenonemonomethylether
GALLACETOPHENONE-4'-METHYL ETHER
Gallacetophenone 4-O-methyl ether
4-METHOXY-2,3-DIHYDROXYACETOPHENONE
2,3-DIHYDROXY-4-METHOXYACETOPHENONE
2,3-Dihydroxy-4-methoxyacetohpenone
Dihydroxymethoxyacetohpenonehydrate
2',3'-DIHYDROXY-4'-METHOXYACETOPHENONE
1-(2,3-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
2',3'-DIHYDROXY-4'-METHOXYACETOHPENONE, HYDRATE
[Molecular Formula]

C9H10O4
[MDL Number]

MFCD00016685
[MOL File]

708-53-2.mol
[Molecular Weight]

182.17
Chemical PropertiesBack Directory
[Melting point ]

133 °C
[Boiling point ]

359.6±42.0 °C(Predicted)
[density ]

1.284±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Room Temperature
[form ]

powder to crystal
[pka]

8.98±0.15(Predicted)
[color ]

Light yellow to Yellow to Green
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332-H315-H319
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
[HS Code ]

2914.50.3000
Hazard InformationBack Directory
[Uses]

1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone is a a neuroprotective compound isolated from Cynenchum paniculatum. It exerts neuroprotective and cognitive-enhancing activities through its antioxidant activity and may be helpful for the treatment of Alzheimer''s disease.
[Preparation]

Preparation by reaction of acetic acid on pyrogallol 1-methyl ether, ? with zinc chloride at reflux (155–160°) (Nencki reaction); ? with boron trifluoride on a steam bath (77%).
[in vivo]

2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1].

Spectrum DetailBack Directory
[Spectrum Detail]

2,3-DIHYDROXY-4-METHOXYACETOPHENONE(708-53-2)MS
2,3-DIHYDROXY-4-METHOXYACETOPHENONE(708-53-2)1HNMR
2,3-DIHYDROXY-4-METHOXYACETOPHENONE(708-53-2)IR1
2,3-DIHYDROXY-4-METHOXYACETOPHENONE(708-53-2)IR2
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