| Identification | More | [Name]
Reboxetine mesylate | [CAS]
71620-89-8 | [Synonyms]
(2r)-2-[(r)-(2-ethoxyphenoxy)phenylmethyl]morpholine
REBOXETINE
REBOXETINE(FORR&DONLY)
REBOXETIN
(2R)-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate
Reboxetine mesylate
(2R*)-2-[(alphaR*)-alpha-(o-Ethoxyphenoxy)benzyl]morpholine mesylate | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C19H23NO3 | [MDL Number]
MFCD00869653 | [Molecular Weight]
313.39 | [MOL File]
71620-89-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
136-139 °C | [Boiling point ]
443.7±30.0 °C(Predicted) | [density ]
1.113±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
Chloroform (Slightly), Water (Slightly) | [form ]
Solid | [pka]
8.37±0.40(Predicted) | [color ]
Off-White to Pale Beige | [CAS DataBase Reference]
71620-89-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Antidepressant (selective noradrenaline reuptake inhibitor). | [Uses]
Reboxetine can be used in biological study of the involvement of monoaminergic neurotransmission in the antidepressant-like action of scopolamine in the tail suspension test. | [Definition]
ChEBI: Reboxetine is an aromatic ether. | [Brand name]
Edronax (Pharmacia & Upjohn). | [Biological Activity]
Potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active, clinically used antidepressant. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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