| Identification | Back Directory | [Name]
DITHIO-BIS-MALEIMIDOETHANE | [CAS]
71865-37-7 | [Synonyms]
Bis(2-maleimidoethyl) Disulfide
1,1'-(Dithiodi-2,1-ethanediyl)bis-1H-pyrrole-2,5-dione
1-[2-[[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]dithio]ethyl]-1H-pyrrole-2,5-dione | [Molecular Formula]
C12H12N2O4S2 | [MDL Number]
MFCD01863385 | [MOL File]
71865-37-7.mol | [Molecular Weight]
312.37 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
124°C | [Boiling point ]
518.6±35.0 °C(Predicted) | [density ]
1.511±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly) | [form ]
powder to crystal | [pka]
-2.05±0.20(Predicted) | [color ]
White to Light yellow | [Stability:]
Temperature Sensitve, Moisture Sensitive | [InChI]
1S/C12H12N2O4S2/c15-9-1-2-10(16)13(9)5-7-19-20-8-6-14-11(17)3-4-12(14)18/h1-4H,5-8H2 | [InChIKey]
SGVWDRVQIYUSRA-UHFFFAOYSA-N | [SMILES]
O=C(C=CC1=O)N1CCSSCCN2C(C=CC2=O)=O |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A sulfhydryl reactive homobifunctional crosslinking reagent.
Spacer Arm: 13.3 Angstroms | [General Description]
DTME is a homobifunctional, maleimide crosslinker for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. DTME is similar in length to BMH but differs in containing a disulfide bond in its spacer arm, allowing crosslinks with DTME to be cleaved with reducing agent such as dithiothreitol (DTT). | [reaction suitability]
reagent type: cross-linking reagent |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [HS Code ]
2930.90.9250 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
|
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TCI Europe
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| Company Name: |
TCI AMERICA
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800-4238616 |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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