ChemicalBook--->CAS DataBase List--->721401-53-2

721401-53-2

721401-53-2 Structure

721401-53-2 Structure
IdentificationBack Directory
[Name]

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-
[CAS]

721401-53-2
[Synonyms]

Rivaroxaban L
Rivaroxaban-12
Decarbonyl Rivaroxaban
Rivaroxaban Impurities358
Rivaroxaban impurity P4D-P
Rivaroxaban Related Impurity G
Rivaroxaban Descarbonyl Impurity
Rivaroxaban descarbonyl imp(G) (pure)
Rivaroxaban Impurity G/ Rivaroxaban Descarbonyl Impurity
Rivaroxaban Descarbonyl Impurity(Crude)/ Rivaroxaban Impurity G
Rivaroxaban Impurity 12/Decarbonyl Rivaroxaban/Rivaroxaban Impurity G
(R)-5-Chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide
2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-
R)-4-chloro-N-(2-hydroxy-3-(4-(3- oxomorpholino)phenylamino)propyl)cyclopen ta-1,3- dienecarboxamide.
Imp. G:5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide
Rivaroxaban Impurity 12/ Decarbonyl Rivaroxaban/5-Chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophencarboxamide
[Molecular Formula]

C18H20ClN3O4S
[MDL Number]

MFCD26227280
[MOL File]

721401-53-2.mol
[Molecular Weight]

409.89
Chemical PropertiesBack Directory
[Melting point ]

>188°C (dec.)
[Boiling point ]

772.6±60.0 °C(Predicted)
[density ]

1.434±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.65±0.46(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
[Major Application]

pharmaceutical small molecule
[InChI]

1S/C18H20ClN3O4S/c19-16-6-5-15(27-16)18(25)21-10-14(23)9-20-12-1-3-13(4-2-12)22-7-8-26-11-17(22)24/h1-6,14,20,23H,7-11H2,(H,21,25)/t14-/m1/s1
[InChIKey]

OKMRQXXUAFSBCM-CQSZACIVSA-N
[SMILES]

[s]1c(ccc1C(=O)NC[C@H](O)CNc2ccc(cc2)N3CCOCC3=O)Cl
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
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