| Identification | Back Directory | [Name]
2-ETHOXY-4-FORMYL-PHENYL ACETATE | [CAS]
72207-94-4 | [Synonyms]
AKOS B004453
ETHYL VANILLIN ACETATE
4-acetoxy-3-ethoxybenzaldehyde
2-ETHOXY-4-FORMYL-PHENYL ACETATE
4-(acetyloxy)-3-ethoxy-benzaldehyd
4-(Acetyloxy)-3-ethoxybenzaldehyde
Benzaldehyde, 4-(acetyloxy)-3-ethoxy-
Acetic Acid 2-Ethoxy-4-formylphenyl Ester
Ethylvanillin acetate,Ethylvanillin,Inhibitor,inhibit | [Molecular Formula]
C11H12O4 | [MDL Number]
MFCD01666413 | [MOL File]
72207-94-4.mol | [Molecular Weight]
208.21 |
| Chemical Properties | Back Directory | [Melting point ]
45 °C | [Boiling point ]
267.4°C (rough estimate) | [density ]
1.0627 (rough estimate) | [refractive index ]
1.4389 (estimate) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [color ]
White to Almost white | [Odor]
at 100.00 %. vanilla milky | [Odor Type]
vanilla | [Water Solubility ]
Soluble in water (986.4 mg / L) at 25°C. | [Sensitive ]
Air Sensitive | [LogP]
2.086 (est) | [CAS DataBase Reference]
72207-94-4 | [EPA Substance Registry System]
Benzaldehyde, 4-(acetyloxy)-3-ethoxy- (72207-94-4) |
| Hazard Information | Back Directory | [Uses]
4-Acetoxy-3-ethoxybenzaldehyde is used in organic synthesis. It is used as catalytic agent; petrochemical additive. | [Synthesis]
3-Ethoxy-4-hydroxybenzaldehyde (50.0 g, 0.30 mol) and triethylamine (Et3N, 39.2 g, 54 mL, 0.39 mol) were dissolved in dichloromethane (DCM, 500 mL) at 0 °C. Acetyl chloride (CH3COCl, 30.6 g, 28 mL, 0.39 mol) was slowly added dropwise to this solution, maintaining the temperature at 0°C. After the dropwise addition was completed, the reaction mixture was continued to be stirred at 0 °C for 30 min. Upon completion of the reaction, the solid product was collected by filtration and the filter cake was washed with dichloromethane. All the filtrates were combined and washed sequentially with water and brine, and the organic layer was dried with anhydrous sodium sulfate (Na2SO4). Finally, the solvent was removed by evaporation to afford the target product 2-ethoxy-4-formylphenyl acetate (62.0 g, 100% yield) as a yellow solid. | [storage]
Store at -20°C | [References]
[1] Patent: WO2014/149793, 2014, A1. Location in patent: Page/Page column 57
[2] Russian Journal of Organic Chemistry, 2005, vol. 41, # 11, p. 1637 - 1646
[3] Russian Journal of General Chemistry, 2005, vol. 75, # 10, p. 1562 - 1565
[4] Russian Journal of Applied Chemistry, 2005, vol. 78, # 1, p. 120 - 124 |
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| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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