| Identification | More | [Name]
Bromoacetaldehyde dimethyl acetal | [CAS]
7252-83-7 | [Synonyms]
2,2-DIMETHOXYETHYL BROMIDE
2-BROMO-1,1-DIMETHOXYETHANE
BADA
BADMA
BROMOACETALDEHYDE DIMETHYL ACETAL
1-Bromo-2,2-dimethoxyethane
2,2-Dimethoxybromoethane
2-bromo-1,1-dimethoxy-ethan
2-Bromoacetaldehyde dimethyl acetal
Acetaldehyde, bromo-, dimethyl acetal
Dimethylbromoacetal
BROMOACETALDEHYDE DIMETHYL ACETAL, STAB.
BROMOACETALDEHYDE DIETHYL ACETAL(2-BROMIDE-1,1-DIETHOXYETHANE)
2-BROMO-1,1-DIMETHYOXYERHANE
BromoacetaldehydeDimethylacetal(Stabilized)97%
2-BROMO-1,1-DIMETHYLETHANE
Bromoacetaldehyde dimethyl acetal, stabilized, 97%
BROMOACETALDEHYDE DIMETHYL ACETAL , STABILIZED WITH POTASSIUM CARBONATE
BROMOACETALDEHYDE DIMETHYL ACETAL (BADA)
Bromoacetaldehyde dimethyl acetal, 97+%, stab. with potassium carbonate | [EINECS(EC#)]
230-669-6 | [Molecular Formula]
C4H9BrO2 | [MDL Number]
MFCD00000213 | [Molecular Weight]
169.02 | [MOL File]
7252-83-7.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colourless to light yellow liquid | [Boiling point ]
148-150 °C (lit.) | [density ]
1.43 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.445(lit.)
| [Fp ]
129 °F
| [storage temp. ]
Refrigerator (+4°C) + Flammables area | [form ]
clear liquid | [color ]
Colorless to Light orange to Yellow | [Specific Gravity]
1.445 | [Water Solubility ]
insoluble | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC | [BRN ]
1280132 | [InChI]
InChI=1S/C4H9BrO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3 | [InChIKey]
FUSFWUFSEJXMRQ-UHFFFAOYSA-N | [SMILES]
C(OC)(OC)CBr | [CAS DataBase Reference]
7252-83-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethane, 2-bromo-1,1-dimethoxy-(7252-83-7) | [EPA Substance Registry System]
7252-83-7(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS02,GHS07 | [Signal word ]
Warning | [Hazard statements ]
H226-H315-H319 | [Precautionary statements ]
P210-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36:Irritating to the eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/39:Wear suitable protective clothing and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1989 3/PG 3
| [WGK Germany ]
3
| [F ]
8-9-21 | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29110000 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2-Dibromo-1-ethoxyethane-->Paraldehyde | [Preparation Products]
1-Benzothiophene-5-carboxylic acid-->Benzofuran-5-boronic acid-->2-(1-Benzothiophen-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane-->(5-Bromo-3-benzo[b]thienyl)methanol-->(5-Chloro-1-benzothiophen-3-yl)methanol-->5-Bromobenzo[b]thiophene-3-carboxylic acid-->5-Chloro-benzo[b]thiophene-3-carboxylic acid-->1-Benzothiophene-5-carbonyl chloride-->1-(1,3-Dioxolan-2-ylmethyl)piperazine-->1-(5-Bromo-1-benzothien-3-yl)ethanone-->3-Acetyl benz[b]thiophene-->1-(5-Chlorobenzo[b]thiophen-3-yl)ethanone-->5-Chlorobenzothiophene-->7-Cyano-benzo[b]thiophene-->2,2'-Methyliminobis-(acetaldehyde dimethyl acetal)-->6,8-Dibromoimidazo[1,2-a]pyrazine-->Methoxyethene-->Oxazole-2-amine-->Benzene, 1-chloro-4-[(2,2-dimethoxyethyl)thio]- |
| Questions And Answer | Back Directory | [Description]
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) is used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization. It is widely used in chemistry for the synthesis of a variety of antibiotics (including erythromycin and cephalosporins) and other drugs. It is an important and highly reactive bifunctional compound with a good leaving group and a masked aldehyde function. It can be used as a starting material in a variety of reactions to provide N-alkylated compounds, lactams, aldehydes, oximes, azides, and acyclic di-/polyselenides.
| [Reference]
Gotkowska, Joanna. "Bromoacetaldehyde Diethyl Acetal." Synlett26.15(2015):2185-2186.
|
| Hazard Information | Back Directory | [Chemical Properties]
clear colourless to light yellow liquid | [Uses]
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) was used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization. |
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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