| Identification | Back Directory | [Name]
Rev 2'-O-MOE-G(iBu)-5'-amidite | [CAS]
725223-44-9 | [Synonyms]
Rev2'-O-MOE-G(iBu)-5'-amidite
Rev 2'-O-MOE-G(iBu)-5'-amidite
3'-O-(4,4’-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-N2-isobutyryl-guanosine-5’-CED phosphoramidite
Guanosine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) | [Molecular Formula]
C47H60N7O10P | [MDL Number]
MFCD32690003 | [MOL File]
725223-44-9.mol | [Molecular Weight]
913.99 |
| Hazard Information | Back Directory | [Uses]
Rev 2’-O-MOE-G(iBu)-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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