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150780-67-9

150780-67-9 Structure

150780-67-9 Structure
IdentificationBack Directory
[Name]

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
[CAS]

150780-67-9
[Synonyms]

2'-OMe-ibu-G Phosphoramidite
ibu-2'-OMe-G Phosphoramidite
2'-OMe-G(ibu) Phosphoramidite
2'-OMe-G(iBu)-3'-phosphoramidit
2'-OMe-G(iBu)-3'-phosphoramidite
5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA
2’-O-Methy-rG(N-ibu)Phosphoramidite
DMT-2'-OME-dG(Bz)-CE-Phosphoramidite
DMT-2′O-Methyl-rG(ib) Phosphoramidite
5'-O-DMT-2'-O-Me-G(ibu) phosporamidite
2'-O-methylguanosine-ce phosphoramidite for abi
N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite
5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite
2'-O-Methyl-N2-Isobutyryl-5'-O-DMT-Guanosine-3'-CE-Phosphoramidite
N2-isobutyryl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
[EINECS(EC#)]

2017-001-1
[Molecular Formula]

C45H56N7O9P
[MDL Number]

MFCD00792625
[MOL File]

150780-67-9.mol
[Molecular Weight]

869.94
Chemical PropertiesBack Directory
[Melting point ]

138 - 140°C
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)
[form ]

powder
[pka]

9.16±0.20(Predicted)
[color ]

white to off-white
[biological source]

non-animal source (no BSE/TSE risk)
[InChIKey]

IRRDHRZUOZNWDJ-MLLDKZSOSA-N
[SMILES]

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

The IUPAC Name is N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
[Uses]

2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.
[Definition]

2'-OMe-G(iBu)-3'-phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis.
[storage]

4°C, protect from light
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