| Identification | Back Directory | [Name]
Dapiprazole Hydrochloride | [CAS]
72822-13-0 | [Synonyms]
AF 2139
Reversil
Rev-eyes
GlaMidolo
Reversil Hydrochloride
Glamidolo Hydrochloride
DAPIPRAZOLE HYDROCHLORIDE
Dapiprazole monohydrochloride
3-(2-(4-(o-tolyl)piperazin-1-yl)ethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine hydrochloride
5,6,7,8-Tetrahydro-3-[2-[4-(2-Methylphenyl)-1-piperazinyl]ethyl]-1,2,4-Triazolo[4,3-a]pyridine Hydrochloride
3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine,hydrochloride
1,2,4-Triazolo(4,3-A)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-, monohydrochloride | [Molecular Formula]
C19H28ClN5 | [MDL Number]
MFCD00941400 | [MOL File]
72822-13-0.mol | [Molecular Weight]
361.912 |
| Chemical Properties | Back Directory | [Description]
Dapiprazole is a new anti-glaucoma agent especially useful in the treatment of narrow-angle glaucoma. It is also reported to have antipsychotic activity potentially devoid of extrapyramidal symptoms. | [Melting point ]
206-207° | [storage temp. ]
2-8°C | [solubility ]
Chloroform, Methanol | [form ]
powder | [color ]
white to beige | [InChI]
1S/C19H27N5.ClH/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19;/h2-3,6-7H,4-5,8-15H2,1H3;1H | [InChIKey]
ZIODNPFQZIHCOE-UHFFFAOYSA-N | [SMILES]
CC1=CC=CC=C1N2CCN(CCC3=NN=C4N3CCCC4)CC2.[H]Cl |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2 | [Toxicity]
LD50 in mice (mg/kg): 260 i.p. (Silvestrini) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Originator]
Angelini (Italy) | [Uses]
Dapiprazole is an alpha blocker. Dapiprazole is used in the reversal of diagnostic mydriasis. | [Brand name]
Glamidolo | [Brand name]
Rev-Eyes (Angelini). | [Biochem/physiol Actions]
Dapiprazole hydrochloride is an an α-adrenergic blocking agent that is used to reverse mydriasis after eye examination. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|