| Identification | Back Directory | [Name]
MIRA-1 | [CAS]
72835-26-8 | [Synonyms]
MIRA-1
NSC 19630
p53 Activator VIII
WRN Helicase Inhibitor
1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2
5-dihydro-1H-pyrrol-1-yl)methyl propionate
Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate
1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]- | [Molecular Formula]
C8H9NO4 | [MDL Number]
MFCD12828765 | [MOL File]
72835-26-8.mol | [Molecular Weight]
183.16 |
| Hazard Information | Back Directory | [Uses]
The tumor suppressor gene, p53, is often mutated in most human cancers. MIRA-1 is a maleimide-derived molecule that can reactivate the mutant p53 leading to apoptosis in human tumor cells. In addition, the MIRA scaffold is an attractive lead for developing anticancer drugs that target mutant p53. | [storage]
Store at +4°C |
|
|