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Janthitrem A is a mycotoxin that has been found in P. janthinellum. It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg. Janthitrem A (20 μg/g) also reduces W. cervinata larvae weight gain and food consumption. | [Uses]
Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae[1]. | [References]
[1] Babu JV, et al. Identification and Structure Elucidation of Janthitrems A and D from Penicillium janthinellum and Determination of the Tremorgenic and Anti-Insect Activity of Janthitrems A and B. J Agric Food Chem. 2018 Dec 19;66(50):13116-13125. DOI:10.1021/acs.jafc.8b04964 |
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