| Identification | Back Directory | [Name]
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol | [CAS]
7448-02-4 | [Synonyms]
Norlanosterol
30-Norlanosterol
14-Norlanosterol
14-demethyl-lanosterol
4,4-Dimethylzymosterol
30-Norlanosta-8,24-dien-3β-ol
30-Nor-8,24-lanostadiene-3β-ol
4,4-dimethyl-cholest-8(9),24-dien-3β-ol
4,4-Dimethyl-5α-cholesta-8,24-dien-3β-ol
Cholesta-8,24-dien-3-ol,4,4-diMethyl-, (3b,5a)-
Cholesta-8,24-dien-3-ol, 4,4-dimethyl-, (3β,5α)-
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
4,4-DIMETHYL-CHOLEST-8(9),24-DIEN-3-OL;14-DEMETHYL-LANOSTEROL | [Molecular Formula]
C29H48O | [MDL Number]
MFCD00945030 | [MOL File]
7448-02-4.mol | [Molecular Weight]
412.69 |
| Chemical Properties | Back Directory | [storage temp. ]
-70°C | [form ]
powder | [InChIKey]
CHGIKSSZNBCNDW-QGBOJXOESA-N | [SMILES]
C[C@]12CCC([C@](CC[C@H](O)C3(C)C)(C)C3CC4)=C4C1CC[C@]2([H])[C@]([H])(C)CCC=C(C)C |
| Hazard Information | Back Directory | [Uses]
14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib. | [Uses]
14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction. | [Definition]
ChEBI: A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol. | [General Description]
14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion. |
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