| Identification | Back Directory | [Name]
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT | [CAS]
74804-12-9 | [Synonyms]
ATP-MG
ATP MAGNESIUM
ATP (dimagnesium)
ATP MAGNESIUM SALT
ATP dimagnesium salt
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT
Adenosine 5'-triphosphate Magnesium Salt (>90%)
adenosine 5'-triphosphate magnesium*from equine M
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUMFROM BACTERIAL
adenosine 5'-triphosphate magnesium salt trihydrate
Adenosine 5'-triphosphate magnesium salt >=95%, bacterial
Adenosine 5′-triphosphate magnesium salt,ATP magnesium salt | [Molecular Formula]
C10H18MgN5O13P3 | [MDL Number]
MFCD00084767 | [MOL File]
74804-12-9.mol | [Molecular Weight]
533.5 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [storage temp. ]
-20°C | [solubility ]
H2O: 50 mg/mL | [form ]
Solid | [color ]
White to Pale Yellow | [biological source]
bacterial | [Water Solubility ]
H2O: 50mg/mL | [Stability:]
Hygroscopic | [InChIKey]
CPGAIACWYFBIFN-UHFFFAOYSA-N | [SMILES]
[Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O |
| Hazard Information | Back Directory | [Uses]
Adenosine 5′-triphosphate magnesium salt has been used:
- as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
- as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
- as a component in action potential intracellular solution
| [Biochem/physiol Actions]
Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. | [in vivo]
ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4].
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo[4].
| Animal Model: | Four-week-old Kunming mice (18-22 g)[4] | | Dosage: | 50 mg/kg | | Administration: | Intraperitoneal injection, before bacterial (E. coli) challenge | | Result: | Protected mice from bacterial infection. |
| [IC 50]
Human Endogenous Metabolite |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1701258/0_EN.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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