| Identification | Back Directory | [Name]
NONYL ACRIDINE ORANGE | [CAS]
75168-11-5 | [Synonyms]
NAO
A-1372
NONYL ACRIDINE ORANGE
10-nonyl Acridine Orange
NONYL-ACRIDINE ORANGE (NAO)
10-NONYLACRIDINE ORANGE BROMIDE
ACRIDINE ORANGE 10-NONYL BROMIDE
Nonyl acridine orange *CAS 75168-11-5*
10-N-NONYL-3,6-BIS(DIMETHYLAMINO)ACRIDINIUM, BR
3,6-BIS(DIMETHYLAMINO)-10-NONYLACRIDINIUM BROMIDE
10-NONYLACRIDINE ORANGE BROMIDE, FOR FLU ORESCENCE
10-NONYLACRIDINE ORANGE BROMIDE FOR FLUORESCENCE 90+%
3,6-bis(dimethylamino)-10-nonylacridin-10-ium bromide
Acridinium, 3,6-bis(dimethylamino)-10-
nonyl-, Bromide
10-Nonylacridine orange bromide, 3,6-Bis(dimethylamino)-10-nonylacridinium bromide | [Molecular Formula]
C26H38BrN3 | [MDL Number]
MFCD00467605 | [MOL File]
75168-11-5.mol | [Molecular Weight]
472.5 |
| Chemical Properties | Back Directory | [Melting point ]
≥250 °C(lit.)
| [storage temp. ]
2-8°C
| [solubility ]
DMSO: soluble
| [form ]
powder | [color ]
Orange-red | [Appearance]
Solid Powder | [ε(extinction coefficient)]
76-88 at 491-497nm in methanol | [λmax]
495 nm | [Biological Applications]
Detecting cardiolipin,mitochondrial membrane potential,risk of type 2 diabetes,cardiotoxicity,prostate cancer; apoptosis assay; drug screening assay; hematotoxicity assay; treating arthritic disorders; in photodynamic ther |
| Hazard Information | Back Directory | [Description]
Acridine orange 10-nonyl is a metachromatic dye that is used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes. | [Uses]
Nonyl acridine orange is well retained in the mitochondria of live HeLa cells for up to 10 days, making it a usefull probe for following mitochondria during isolation and after cell fusion. This dye has been used to analyze mitochondria by flow cytometry, | [in vivo]
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm) which can be used to quantify the cardiolipin in isolated mitochondria[1]. when Acridine Orange 10-Nonyl Bromide interacts with cardiolipin, the dye excitation and emission wave lengths shift from 496 and 525 nm to 450 and 640 nm, respectively. Increasing amounts of cardiolipin (0 to 30 μM) and other acidic phospholipids in thin-walled vesicles added to Acridine Orange 10-Nonyl Bromide (45 μM) changes the red fluorescence emission measured at 640 nm according to the liposome composition[2]. | [Excitation / Emission Maximum]
490 nm/510 nm |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|