| Identification | Back Directory | [Name]
3-FLUOROPHENETHYL ALCOHOL | [CAS]
75321-89-0 | [Synonyms]
2-(M-FLUOROPHENYL)ETHANOL
3-fluoroBenzeneacetaldehyde
(3-FLUORO-PHENYL)-ACETALDEHYDE
2-(3-fluorophenyl)acetaldehyde
Benzeneacetaldehyde, 3-fluoro- | [Molecular Formula]
C8H7FO | [MDL Number]
MFCD02261760 | [MOL File]
75321-89-0.mol | [Molecular Weight]
138.14 |
| Chemical Properties | Back Directory | [Boiling point ]
90 °C3 mm Hg(lit.) | [density ]
1.125 g/mL at 25 °C(lit.) | [refractive index ]
n20/D 1.509(lit.) | [Fp ]
225 °F | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
solid |
| Hazard Information | Back Directory | [Synthesis]
2-(3-Fluorophenyl)acetaldehyde was synthesized by oxidation reaction using 3-fluorophenethyl alcohol as starting material. The steps were as follows: 1. 3-Fluorophenyl ethanol was reacted with an oxidizing agent (e.g., PCC or Swern oxidizing reagent) in a suitable solvent at 0 °C to room temperature. 2. After completion of the reaction, the target product, 2-(3-fluorophenyl)acetaldehyde, was obtained by extraction and purification by column chromatography. This synthetic route is efficient and selective and is suitable for laboratory scale preparation. | [References]
[1] Patent: WO2008/36294, 2008, A2. Location in patent: Page/Page column 4; 6/8
[2] Patent: WO2008/42353, 2008, A1. Location in patent: Page/Page column 35; 41-42
[3] Journal of Medicinal Chemistry, 2009, vol. 52, # 3, p. 779 - 797
[4] Patent: WO2012/97121, 2012, A2. Location in patent: Page/Page column 14
[5] Patent: WO2008/42353, 2008, A1. Location in patent: Page/Page column 35; 41-42 |
|
| Company Name: |
Fluoropharm Co., Ltd.
|
| Telephone: |
0571-85586753 13336034509 |
| Website: |
http://www.fluoropharm.com |
| Company Name: |
Henan Alpha Chemical Co., Ltd.
|
| Telephone: |
0371-55055611 18137792234 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList31206/0.htm |
|