| Identification | Back Directory | [Name]
alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) | [CAS]
756525-99-2 | [Synonyms]
N-Succinim
Mal-PEG4-NHS
Mal-NH-PEG4-NHS
Mal-amido-PEG4-NHS
MAL-DPEG4-NHS Ester
Mal-NH-PEG4-NHS ester
MAL-NH-PEG4-CH2CH2COONHS
Maleimide-PEG4-NHS Ester
Maleimide-PEG4-succinimidyl Ester
Maleimide-NH-PEG4-CH2CH2COONHS Ester
Maleimidopropionyl-PEG4-CH2CH2COONHS Ester
alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)
3-(2-Maleimidoethylcarbamoyl)-peg4-propionic acid N-hydroxysuccinimide ester
O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol
O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol >=90% (NMR)
2,5-dioxopyrrolidin-1-yl 19-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-oate
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate
N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | [EINECS(EC#)]
201-258-5 | [Molecular Formula]
C22H31N3O11 | [MDL Number]
MFCD11041113 | [MOL File]
756525-99-2.mol | [Molecular Weight]
513.49 |
| Chemical Properties | Back Directory | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
15.01±0.46(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C22H31N3O11/c26-17(5-8-24-18(27)1-2-19(24)28)23-7-10-33-12-14-35-16-15-34-13-11-32-9-6-22(31)36-25-20(29)3-4-21(25)30/h1-2H,3-16H2,(H,23,26) | [InChIKey]
XSRYGQJQNPJNKZ-UHFFFAOYSA-N | [SMILES]
C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O |
| Hazard Information | Back Directory | [Description]
Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Uses]
Maleimide-PEG4-NHS (CAS# 756525-99-2) is a cross-linking compound used in the lysosomal acid-triggered release of anticancer drugs. | [reaction suitability]
reagent type: cross-linking reagent | [IC 50]
PEGs; Alkyl/ether |
|
|